
Our Published Research
Our NeuropathyDR® treatment systems, NDGen® neurostimulation technology, and clinical protocols have been published in internationally recognized peer-reviewed medical journals including EC Neurology.
“A Comparison of the Clinical Effectiveness of Specific Neurostimulation and Photobiomodulation Modalities with Therapeutic Nutrition in the Treatment of Peripheral Neuropathy”
Abstract: Peripheral neuropathy (PN) is a severe condition with numerous comorbidities. Approximately 4% of adults and the elderly develop polyneuropathy of various etiologies. Many pharmacological agents are inadequate in treating PN and carry significant side effects.
This retrospective study reports a comparison of the clinical effectiveness of specific neurostimulation and photobiomodulation (low-level laser) modalities combined with therapeutic nutrition. Most participants reported symptom relief with each component, while neurostimulation provided nearly universal relief of all PN symptoms in the participants surveyed.
“Non-Pharmacologic Care and Management of Neuropathy”
Authors: Nicholas A Kerna, John V Flores, Hilary M Holets, Lawrence U Akabike, Mark H Chen, Emmanueulla Olubunmi Solomon, Kevin D Pruitt, John Hayes Jr, MD, Shain Waugh
Journal: EC Neurology 13.2 (2021): 67-76
Abstract: According to the International Association for the Study of Pain (IASP), neuropathic pain is caused by a primary lesion or dysfunction of the nervous system. Common modalities explored include chronic degenerative, post-traumatic, diabetic, and peripheral neuropathies.
This research explores non-pharmacologic care and management of peripheral neuropathy. The non-invasive, multi-modal therapies seem promising when used alone or in combination as conjunctive therapies with conventional treatment.

John Hayes Jr., MD
Co-Founder NeuropathyDR® & Co-Designer NDGen®
John Hayes Jr. MD — Pioneer in Neuromusculoskeletal & Direct Primary Care
John is a Board Certified Family & Lifestyle Medicine Physician who spent years prior as a chiropractor & nutritionist working primarily with physicians and surgeons.
He helped thousands during illness, surgeries, and debilitating spine and joint pain regain their health through comprehensive care often including manual therapy, nutrition, and laser. Years of research led to the development of his company NeuropathyDR® and the NDGen® treatment systems now used worldwide to better help those suffering from neuropathy, chronic pain & related illness.
His work with the sickest led to the completion of Medical School (USAT, Montserrat), where he graduated Summa Cum Laude. John completed his Family & Lifestyle Medicine Residency at St. Luke's Anderson in Easton, PA. He is the first ever MD to complete their Osteopathic Training program as well.
Research Focus Areas
The three pillars of the NeuropathyDR® protocol, validated through published clinical research.
Microvascular Vasodilation
Restoring capillary blood supply to ischemic peripheral nerves to reverse oxygen starvation at the root of nerve breakdown.
Electrotherapeutic Stimulation
Promoting neuro-regeneration and blocking pain signals non-pharmacologically through NDGen calibrated nerve stimulation protocols.
Metabolic Stabilization
Addressing nutritional and glycemic co-factors in diabetic and metabolic neuropathies to halt progression and support recovery.
Key Clinical Findings
- ✓Microvascular Vasodilation: Restoring capillary blood supply to ischemic peripheral nerves.
- ✓Electrotherapeutic Stimulation: Promoting neuro-regeneration and blocking pain signals non-pharmacologically.
- ✓Metabolic Stabilization: Addressing nutritional and glycemic co-factors in diabetic and metabolic neuropathies.
Experience the Protocol Backed by Published Science
Connect with a NeuropathyDR certified treatment center and begin a research-driven recovery plan tailored to your condition.






