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NeuropathyDR The number one neuropathy and chronic pain treatment centers patients and professionals turn to for answers
Research background
Peer-Reviewed Science & Clinical Evidence

Our Published Research

Our NeuropathyDR® treatment systems, NDGen® neurostimulation technology, and clinical protocols have been published in internationally recognized peer-reviewed medical journals including EC Neurology.

Primary Clinical Trial PublicationPublished: May 13, 2020

“A Comparison of the Clinical Effectiveness of Specific Neurostimulation and Photobiomodulation Modalities with Therapeutic Nutrition in the Treatment of Peripheral Neuropathy”

Authors: John Hayes Jr, MD1,2, Shannon Boyce, JD1, Nicholas A. Kerna, PhD, MD3
Affiliations: 1NeuropathyDR®, USA | 2USAT Montserrat | 3SMC Medical Research

Abstract: Peripheral neuropathy (PN) is a severe condition with numerous comorbidities. Approximately 4% of adults and the elderly develop polyneuropathy of various etiologies. Many pharmacological agents are inadequate in treating PN and carry significant side effects.

This retrospective study reports a comparison of the clinical effectiveness of specific neurostimulation and photobiomodulation (low-level laser) modalities combined with therapeutic nutrition. Most participants reported symptom relief with each component, while neurostimulation provided nearly universal relief of all PN symptoms in the participants surveyed.

82%+
Symptom Improvement in Compliant Patients
15+ Yrs
Clinical Field Testing & Development
10,000+
Patients Evaluated Worldwide
Read Full Study on ResearchGate
EC Neurology Journal PublicationCitation: EC Neurology 13.2 (2021): 67-76

“Non-Pharmacologic Care and Management of Neuropathy”

Authors: Nicholas A Kerna, John V Flores, Hilary M Holets, Lawrence U Akabike, Mark H Chen, Emmanueulla Olubunmi Solomon, Kevin D Pruitt, John Hayes Jr, MD, Shain Waugh

Journal: EC Neurology 13.2 (2021): 67-76

Abstract: According to the International Association for the Study of Pain (IASP), neuropathic pain is caused by a primary lesion or dysfunction of the nervous system. Common modalities explored include chronic degenerative, post-traumatic, diabetic, and peripheral neuropathies.

This research explores non-pharmacologic care and management of peripheral neuropathy. The non-invasive, multi-modal therapies seem promising when used alone or in combination as conjunctive therapies with conventional treatment.

John Hayes Jr. MD
Lead Clinical Researcher

John Hayes Jr., MD

Co-Founder NeuropathyDR® & Co-Designer NDGen®

About The Lead Investigator

John Hayes Jr. MD — Pioneer in Neuromusculoskeletal & Direct Primary Care

John is a Board Certified Family & Lifestyle Medicine Physician who spent years prior as a chiropractor & nutritionist working primarily with physicians and surgeons.

He helped thousands during illness, surgeries, and debilitating spine and joint pain regain their health through comprehensive care often including manual therapy, nutrition, and laser. Years of research led to the development of his company NeuropathyDR® and the NDGen® treatment systems now used worldwide to better help those suffering from neuropathy, chronic pain & related illness.

His work with the sickest led to the completion of Medical School (USAT, Montserrat), where he graduated Summa Cum Laude. John completed his Family & Lifestyle Medicine Residency at St. Luke's Anderson in Easton, PA. He is the first ever MD to complete their Osteopathic Training program as well.

Summa Cum Laude Medical School Honors
St. Luke's Osteopathic Trained MD
South Shore Direct Primary Care & Integrative Clinic
Physician & Physical Therapist Trainer

Research Focus Areas

The three pillars of the NeuropathyDR® protocol, validated through published clinical research.

Microvascular Vasodilation

Restoring capillary blood supply to ischemic peripheral nerves to reverse oxygen starvation at the root of nerve breakdown.

Electrotherapeutic Stimulation

Promoting neuro-regeneration and blocking pain signals non-pharmacologically through NDGen calibrated nerve stimulation protocols.

Metabolic Stabilization

Addressing nutritional and glycemic co-factors in diabetic and metabolic neuropathies to halt progression and support recovery.

Key Clinical Findings

  • ✓Microvascular Vasodilation: Restoring capillary blood supply to ischemic peripheral nerves.
  • ✓Electrotherapeutic Stimulation: Promoting neuro-regeneration and blocking pain signals non-pharmacologically.
  • ✓Metabolic Stabilization: Addressing nutritional and glycemic co-factors in diabetic and metabolic neuropathies.
Research-Backed Care

Experience the Protocol Backed by Published Science

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